下面哪个诺贝尔奖的研究采用的是反向遗传学策略：

A．Andrew Z. Fire and Craig C. Mello, 2006
B．Sydney Brenner, H. Robert Horvitz and John E. Sulston, 2002
C．Hermann Joseph Muller, 1946
D．Edward B. Lewis, Christine Nusslein-Volhard and Eric F. Weischaus, 1995