A 40-year-old woman comes to the physician for an annual examination. She has no complaints. She has menses every 28-30 days that last for 3 days. She has no intermenstrual bleeding. She has asthma, for which she uses an occasional inhaler. She had a tubal ligation 10 years ago. She has no known drug allergies. Examination is unremarkable, including a normal pelvic examination. One of her friends was recently diagnosed with endometrial cancer, and the patient wants to know when and if she needs to be screened for this. Which of the following is the most appropriate response?
A、Screening for endometrial cancer is not cost effective or warranted 
B、Screening is with endometrial biopsy and starts at age 40
C、Screening is with endometrial biopsy and starts at age 50
D、 Screening is with ultrasound and starts at age 40
E、Screening is with ultrasound and starts at age 50