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单项选择题

A 25-year-old man presents because of ‘fullness’ in his neck. Physical examination finds enlargement of the thyroid gland resulting from the presence of several small masses in both thyroid lobes. These nodules are surgically resected, and the pathology report from this surgical specimen diagnoses a papillary carcinoma. Which of the following histologic changes is most characteristic of this type of carcinoma? A.  An amyloid stroma B. Bland micro-follicles C. Extracellular Russell bodies D. Neoplastic C cells E. Orphan Annie nuclei

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