单项选择题

Which of the following is correct about Atg1/ULK complex?

A．The ATG-ULK complex is implicated in the early events of autophagosome biogenesis
B．The Atg1/ULK complex, consisting of Atg1, Atg13, and a dimer of Atg17-Atg31-Atg29, associates with membranes at the phagophore assembly site (PAS).
C．Autophagy induction requires the activation of the Atg1 kinase activity, which is under the direct control of both mammalian target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK)
D．All of the above

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